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Updated: Jun 22, 2026
Surgical Training for the Implantation of Neocortical Microelectrode Arrays Using a Formaldehyde-fixed Human Cadaver Model
Published on: November 19, 2017
Human neocortical electrical activity recorded on nonpenetrating microwire arrays: applicability for neuroprostheses
Spencer S Kellis1, Paul A House, Kyle E Thomson
1Department of Electrical and Computer Engineering, University of Utah, Salt Lake City, Utah, USA.
Object:
The goal of this study was to determine whether a nonpenetrating, high-density microwire array could provide sufficient information to serve as the interface for decoding motor cortical signals.
Methods:
Arrays of nonpenetrating microwires were implanted over the human motor cortex in 2 patients. The patients performed directed stereotypical reaching movements in 2 directions. The resulting data were used to determine whether the reach direction could be distinguished through a frequency power analysis.
Results:
Correlation analysis revealed decreasing signal correlation with distance. The gamma-band power during motor planning allowed binary classification of gross directionality in the reaching movements. The degree of power change was correlated to the underlying gyral pattern.
Conclusions:
The nonpenetrating microwire platform showed good potential for allowing differentiated signals to be recorded with high spatial fidelity without cortical penetration.
