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Two flavonoid dimers from Sarcandra hainanensis (PEI) SWAMY et BAILEY
Cong-Mei Cao1, Yong Peng, Li-Jia Xu
1Institute of Medicinal Plant Development, Chinese Academy of Medical Science, Peking Union Medical College.
Chemical & Pharmaceutical Bulletin
|July 3, 2009
Abstract:
Two new flavonoid dimers (1, 2) consisting of flavan-chalcone together with three known compounds (3-5) were isolated from the ethanol extract of the whole plants of Sarcandra hainanensis. Their structures were determined by extensive spectroscopic analysis. Human immunodeficiency virus-1 integrase inhibition activities of compounds 1 and 2 were evaluated and they showed weak activities with IC(50) at 18.05 and 25.27 muM, respectively.
