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Updated: Jun 22, 2026

Diffusion Tensor Magnetic Resonance Imaging in the Analysis of Neurodegenerative Diseases

Diffusion Tensor Magnetic Resonance Imaging in the Analysis of Neurodegenerative Diseases

Published on: July 28, 2013

White matter atlases based on diffusion tensor imaging.

Susumu Mori¹, Kenichi Oishi, Andreia V Faria

¹Division of NMR Research, The Russell H. Morgan Department of Radiology and Radiological Science, The Johns Hopkins University School of Medicine, Baltimore, Maryland 21205, USA. Susumu@mri.jhu.edu

Current Opinion in Neurology

|July 3, 2009

Summary

This summary is machine-generated.

Diffusion tensor imaging (DTI) advances white matter research by enabling detailed axonal tract delineation. New analysis tools enhance understanding of white matter structure and abnormalities.

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Last Updated: Jun 22, 2026

Diffusion Tensor Magnetic Resonance Imaging in the Analysis of Neurodegenerative Diseases

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Published on: July 28, 2013

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Published on: August 26, 2014

Co-analysis of Brain Structure and Function using fMRI and Diffusion-weighted Imaging

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Published on: November 8, 2012

Area of Science:

Neuroimaging
Neuroanatomy
Medical Imaging Analysis

Background:

Diffusion Tensor Imaging (DTI) offers unique noninvasive visualization of white matter axonal tracts.
Significant advancements in DTI technology and analysis tools have emerged in the last decade.
Previous imaging techniques lacked the resolution to delineate specific white matter pathways.

Purpose of the Study:

To review recent advancements in Diffusion Tensor Imaging (DTI) studies.
To provide an overview of novel image analysis tools for DTI data.
To highlight the expanding anatomical knowledge derived from DTI.

Main Methods:

Characterization of white matter anatomy using DTI.
Parcellation of white matter into constituent tracts based on orientation and anisotropy.
Extrapolation of DTI data for three-dimensional connectivity mapping.

Main Results:

DTI enables detailed characterization of white matter anatomy.
White matter tracts can be identified and mapped using DTI.
New DTI-based analysis tools facilitate investigation of white matter integrity.

Conclusions:

DTI allows for the study of intra-white matter structures, moving beyond a single-compartment view.
Advanced analysis tools deepen the understanding of white matter organization.
DTI aids in investigating white matter abnormalities in pathological conditions.