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Updated: Jun 22, 2026

Quantitative Structure-Activity Relationship, Activity Prediction, and Molecular Dynamics of Non-nucleotide Reverse Transcriptase Inhibitors
Published on: May 9, 2025
[Pharmacoeconomic aspects of lopinavir/ritonavir monotherapy]
Ismael Escobar Rodríguez1, Concepción Esteban Alba
1Servicio de Farmacia, Hospital Infanta Leonor, Servicio Madrileño de Salud, Madrid, España. iescobar@sefh.es
Abstract:
The present article briefly reviews the main types of pharmacoeconomic analyses that evaluate the costs associated with HIV infection and the efficiency of antiretroviral therapy in general. The results of several pharmacoeconomic analyses applied to the selection of antiretroviral drugs in distinct clinical scenarios are also presented. Finally, we analyze the advantages, in terms of efficiency, of lopinavir/ritonavir as induction-maintenance therapy, both in terms of saving the direct costs of treatment and in possibly reducing the costs due to the management of the adverse effects of nucleoside analogs.
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