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Comparison of Agreement and Accuracy using Binocular Wavefront Optometer with Autorefractor and Phoropter
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Ocular wavefront aberrations in patients with macular diseases
Kenichiro Bessho1, Dirk-Uwe G Bartsch, Laura Gomez
1Department of Ophthalmology, University of California San Diego, Jacobs Retina Center/Shiley Eye Center, La Jolla, California 92093-0946, USA.
Retina (Philadelphia, Pa.)
|July 4, 2009
Summary
Patients with macular disease exhibit greater ocular wavefront aberrations than healthy individuals. This finding is crucial for developing adaptive optics systems to improve retinal imaging resolution in diseased eyes.
Area of Science:
- Ophthalmology
- Optical Engineering
Background:
- Adaptive optical systems may enhance clinical retinal imaging resolution by compensating for ocular aberrations.
- Understanding ocular wavefront aberrations in retinal disease is essential for developing these systems.
Purpose of the Study:
- To investigate and quantify ocular wavefront aberrations in patients with macular disease compared to healthy controls.
Main Methods:
- Wavefront aberrations were measured in 82 eyes of 66 patients with macular disease and 85 eyes of 51 controls using a ray-tracing wavefront device.
- Zernike coefficients up to the sixth order were acquired for both small and large pupil apertures.
Main Results:
- Eyes with macular disease showed statistically greater third-order root mean square errors than control eyes.
- This increase was observed in both phakic (12-31%) and pseudophakic (51-57%) eyes across different scan diameters.
Conclusions:
- Higher-order wavefront aberrations are more pronounced in eyes with macular disease, potentially due to irregular retinal surfaces.
- Advancements in wavefront sensor technology are necessary for accurate aberration measurement and adaptive optics correction in eyes with macular irregularities.
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