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Published on: May 10, 2019
Alterations in early auditory evoked potentials in multiple sclerosis patients
Tania Mara Assis Lima1, Aline Nascimento Crato, Patrícia Cotta Mancini
1Department of Otorhinolaryngology, FM, UFMG
Brazilian Journal of Otorhinolaryngology
|July 4, 2009
Summary
Early auditory evoked potentials (EAEP) can indicate brainstem lesions in demyelinating diseases. This study found that 36% of multiple sclerosis patients had altered EAEP, highlighting the need for auditory testing in MS diagnosis and management.
Area of Science:
- Neurology
- Audiology
- Neurophysiology
Background:
- Demyelinating diseases, such as multiple sclerosis (MS), can affect the central nervous system.
- Alterations in early auditory evoked potentials (EAEP) are associated with brainstem lesions.
Purpose of the Study:
- To determine the prevalence of hearing disorders and abnormal EAEP in patients diagnosed with multiple sclerosis.
- To investigate the utility of EAEP as a diagnostic marker in MS.
Main Methods:
- A cohort of 25 patients (16 female, 9 male) with confirmed multiple sclerosis diagnosis participated.
- All participants underwent comprehensive hearing assessments and EAEP testing.
- Auditory evoked potential waveforms were classified using Jerger's criteria (1986).
Main Results:
- Out of 50 EAEP tests, 70% showed normal responses (Type I).
- Altered EAEP results (Types II-V) were observed in 36% of the patients.
- Hearing alterations were noted in 31.25% of females and 44.44% of males.
Conclusions:
- EAEP testing is valuable for identifying auditory pathway involvement in demyelinating diseases.
- Routine EAEP assessment should be considered for patients with suspected or diagnosed multiple sclerosis.
- Abnormal EAEP may serve as an indicator of brainstem lesions in MS patients.
