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Updated: Jun 21, 2026

An Adoptive Transfer Model of Rheumatoid Arthritis in Mice
Published on: June 6, 2025
Infectious aspects and the etiopathogenesis of rheumatoid arthritis
Michal Kasher Meron1, Howard Amital, Daniel Shepshelovich
1Department of Medicine D, Meir Medical Center affiliated with Tel Aviv University Sackler Faculty of Medicine, Kfar-Saba, Israel.
Abstract:
Infections are believed to contribute to the maturation of the immune system from the innate to the adaptive phases and therefore may take part in the induction of autoimmune conditions. In the current study, we present an extensive analysis conducted on sera samples of patients with rheumatoid arthritis in order to seek evidence of previous or coexisting infectious processes using the Bio-Rad BioPlex immunoassay analyzer. We detected higher rates of serological evidence of infections with Epstein-Barr virus and cytomegalovirus viruses. Our findings may indicate a role of these viruses in the pathogenesis of RA.
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