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Cell Adhesion in Plants

Cell Adhesion in Plants

Plants have rigid cell walls that are made up of cell wall polysaccharides that mediate cell-cell adhesion. The primary cell walls of plants consist of two independent and interacting polysaccharide networks: a pectin matrix that embeds the second network comprising cellulose and hemicelluloses.
Pectins are complex heteropolymers mainly composed of negatively-charged α-D-glucopyranosyl uronic acid and some neutral glycosyl residues such as α-L-rhamnopyranose, α-L-arabinofuranose, and...

Adhesion

Adhesion

Adhesion occurs when one type of molecule is attracted to a different molecule. Water exhibits adhesive properties in the presence of polar surfaces, such as glass or cellulose in plants. For instance, when water is poured into a glass, the positively charged hydrogen molecules of water are more attracted to the negatively charged oxygen molecules in the silica than to the oxygen in neighboring water molecules.
Capillary action is a result of water’s adhesive tendencies. When a narrow glass...

Cell Adhesion Molecules - Types and Functions

Cell Adhesion Molecules - Types and Functions

Cell adhesion molecules (CAMs) are pivotal to multicellularity and the coordinated functioning of tissues and organ systems. They enable physical interactions between cells and provide mechanical strength to tissues. They also function as receptors for signal transmission across the plasma membrane. The CAMs are broadly classified into four families - integrins, cadherins, selectins, and immunoglobulin-like CAMs (IgCAMs).
CAM Families
The Integrin family of proteins is primarily involved in a...

Cell Adhesion Molecules - Types and Functions

Cell Adhesion Molecules - Types and Functions

Cell adhesion molecules (CAMs) are pivotal to multicellularity and the coordinated functioning of tissues and organ systems. They enable physical interactions between cells and provide mechanical strength to tissues. They also function as receptors for signal transmission across the plasma membrane. The CAMs are broadly classified into four families - integrins, cadherins, selectins, and immunoglobulin-like CAMs (IgCAMs).
CAM Families
The Integrin family of proteins is primarily involved in a...

Cell Migration

Cell Migration

Cell migration is a process by which the cells move from one location to another, playing an essential role in embryological development, repair and regeneration, immune response, and metastasis. Cells migrate in response to chemical or mechanical signals generated by specific organs or tissues. The overall mechanism includes three steps - polarization, protrusion, and release. Polarization involves the formation of a distinct cell front and rear, which determines the direction of movement.

Cell Migration

Cell Migration

Cell migration, the process by which cells move from one location to another, is essential for the proper development and viability of organisms throughout their life. When cells are not able to migrate properly to their ordained locations, various disorders may occur. For example, disruption in cell migration causes chronic inflammatory diseases such as arthritis.

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Related Experiment Video

Updated: Jun 21, 2026

Imaging Molecular Adhesion in Cell Rolling by Adhesion Footprint Assay

Imaging Molecular Adhesion in Cell Rolling by Adhesion Footprint Assay

Published on: September 27, 2021

Rolling cell adhesion.

Rodger P McEver¹, Cheng Zhu

¹Cardiovascular Biology Research Program, Oklahoma Medical Research Foundation, Department of Biochemistry and Molecular Biology, University of Oklahoma Health Sciences Center, Oklahoma City, Oklahoma 73104, USA. rodger-mcever@omrf.org

Annual Review of Cell and Developmental Biology

|July 7, 2009

Summary

This summary is machine-generated.

Cell adhesion receptors use unique "catch bonds" that strengthen under force, enabling flow-enhanced rolling important for immune cell trafficking and vascular interactions.

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Last Updated: Jun 21, 2026

Imaging Molecular Adhesion in Cell Rolling by Adhesion Footprint Assay

Imaging Molecular Adhesion in Cell Rolling by Adhesion Footprint Assay

Published on: September 27, 2021

Studying Cell Rolling Trajectories on Asymmetric Receptor Patterns

Studying Cell Rolling Trajectories on Asymmetric Receptor Patterns

Published on: February 13, 2011

Systematic Analysis of In Vitro Cell Rolling Using a Multi-well Plate Microfluidic System

Systematic Analysis of In Vitro Cell Rolling Using a Multi-well Plate Microfluidic System

Published on: October 16, 2013

Area of Science:

Biophysics
Cell Biology
Immunology

Background:

Cellular rolling adhesion is critical for immune cell and platelet recruitment to vascular sites.
This process involves dynamic formation and dissociation of adhesive bonds under blood flow shear stress.
Understanding the mechanical regulation of these bonds is key to comprehending cellular trafficking.

Purpose of the Study:

To review the mechanisms by which adhesion receptors utilize mechanically regulated kinetics.
To explore the role of catch bonds in flow-enhanced rolling adhesion.
To elucidate how receptor structure, clustering, and signaling influence adhesion dynamics.

Main Methods:

Review of existing literature on cell adhesion receptor mechanics.
Analysis of biophysical principles governing bond kinetics under force.
Examination of structural and signaling pathways modulating adhesion receptor function.

Main Results:

Adhesion receptors exhibit force-dependent bond lifetimes, including catch bonds (strengthen with force) and slip bonds (weaken with force).
Catch bonds explain the phenomenon of flow-enhanced rolling adhesion.
Force-regulated disruptions in receptor domains and interactions with cytoskeleton/membrane domains are key to catch bond formation.
Cellular signals (inside-out and outside-in) regulate these force-dependent adhesion processes.

Conclusions:

Mechanically regulated catch bonds are a fundamental mechanism for efficient cellular rolling adhesion in blood flow.
The interplay between receptor structure, force, and cellular signaling dictates adhesion dynamics.
This understanding has implications for immune response, vascular injury, and progenitor cell trafficking.