[Clinical research of accommodating intraocular lens]

To assess the visual outcomes and accommodative amplitude of accommodating intraocular lens (AIOL).

Case control study. Thirty eyes of 22 patients with cataracts had undergone phacoemulsification and implantation of AIOL. Twenty nine eyes of 22 age- and sex-matched patients with cataracts had the same surgery but foldable acrylic IOL were used as the controls. All patients were assessed for accommodation amplitude, visual acuity and for change of anterior chamber depth (ACD) at 6 and 12 months after surgery. Accommodation amplitude was measured using the pushing-up test. The change of ACD was measured with OCULUS Pentacam analysis system.

During the follow-up time, the patients in the test group had better uncorrected near vision acuity (UCNV) and distance corrected near vision acuity (DCNVA)(P = 0.000). The test group had the same corrected vision acuity as the control group. Six months after surgery, push-up test showed that the mean accommodative amplitude was (1.60 +/- 0.57) D in the test group and (1.10 +/- 0.70) D in the control group. The change of the ACD was (0.50 +/- 0.37) mm in the test group and (0.08 +/- 0.06) mm in the control group. Twelve months after surgery, push-up test showed that the mean accommodative amplitude was (1.38 +/- 0.52) D in the test group and (1.06 +/- 0.61) D in the control group. The change of the ACD was (0.30 +/- 0.27) mm in the test group and (0.10 +/- 0.09) mm in the control group.

In the present study, the Tetraflex AIOL showed greater accommodative amplitude and better near visual acuity than those of the control group with conventional IOL. But 6 months later, all of these measurements in the test group were decreased.