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Published on: August 19, 2020
Delirium: an emerging frontier in the management of critically ill children
Heidi A B Smith1, D Catherine Fuchs, Pratik P Pandharipande
1Pediatrics and Anesthesiology Division of Critical Care, Department of Pediatrics, 5121 Doctor's Office Tower, 2200 Children's Way, Nashville, TN 37232-9075, USA. heidi.smith@vanderbilt.edu
Insights
This article explains pediatric delirium, a type of acute brain dysfunction. It covers diagnosis, prevalence, pathophysiology, and management strategies for critically ill children.
Area of Science:
- Pediatric Critical Care Medicine
- Neuroscience
- Intensive Care Medicine
Background:
- Delirium, characterized by acute brain dysfunction, affects critically ill patients.
- Understanding and diagnosing delirium in children presents unique challenges compared to adults.
Purpose of the Study:
- To introduce pediatric delirium, including its classification and clinical presentations.
- To discuss diagnostic approaches for delirium in critically ill children, drawing from adult critical care.
- To review the prevalence, prognostic significance, pathophysiology, and management of pediatric delirium.
Main Methods:
- Literature review and synthesis of existing research on delirium in adult and pediatric populations.
- Analysis of diagnostic criteria and their applicability to pediatric intensive care settings.
- Compilation of current understanding of delirium pathophysiology and evidence-based management.
Main Results:
- Pediatric delirium is an acute brain dysfunction with specific clinical presentations.
- Diagnostic tools and understanding of delirium in adults can be translated to pediatric care.
- Delirium is prevalent in critically ill children and has significant prognostic implications.
Conclusions:
- Early recognition and diagnosis of pediatric delirium are crucial for appropriate management.
- Further research is needed to refine diagnostic and management strategies tailored to pediatric populations.
- Addressing delirium in critically ill children can improve outcomes and reduce long-term sequelae.
Abstract:
The objectives of this article are (1) to introduce pediatric delirium and provide understanding of acute brain dysfunction with its classification and clinical presentations (2) to understand how delirium is diagnosed and discuss current modes of delirium diagnosis in the critically ill adult population and translation to pediatrics (3) to understand the prevalence and prognostic significance of delirium in the adult and pediatric critically ill population (4) to discuss the pathophysiology of delirium as currently understood, and (5) to provide general management guidelines for delirium.
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