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Renal failure in patients with cirrhosis
Lina Mackelaite1, Zygimantas C Alsauskas, Karthik Ranganna
1Division of Nephrology, Department of Medicine, Drexel University College of Medicine, 245 North 15th Street, Room 6144, Philadelphia, PA 19102, USA.
Abstract:
Renal failure in cirrhosis poses unique diagnostic and therapeutic challenges. Laboratory values and predictive equations grossly overestimate renal function in patients with cirrhosis. Development of renal failure connotes a worse prognosis; mortality is especially high with hepatorenal syndrome. Classification of the causes of renal failure in patients with cirrhosis is provided with more extensive discussion of selected causes. Finally, a suggested diagnostic approach to renal failure in cirrhosis is given.
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