Outcomes of surgically managed pediatric thyroid cancer

Anna E Bargren1, Goswin Y Meyer-Rochow, Leigh W Delbridge

  • 1Section of Endocrine Surgery, Department of Surgery, University of Wisconsin, Madison, WI 53792, USA.

Insights

Pediatric thyroid cancer management via total thyroidectomy is recommended. While surgical complications were similar across procedures, less-than-total thyroidectomies increased the risk of repeat surgeries for children.

Area of Science:

  • Pediatric Surgery
  • Endocrine Surgery
  • Oncology

Background:

  • Thyroid cancer is the most common childhood carcinoma, often presenting at a more advanced stage than in adults.
  • Current management for pediatric and adult thyroid cancer is similar, predominantly involving total thyroidectomy.
  • The study aimed to evaluate surgical outcomes specifically in pediatric patients with thyroid malignancy.

Purpose of the Study:

  • To investigate the surgical outcomes of pediatric patients undergoing treatment for thyroid malignancy.
  • To compare complication rates and the need for reoperation based on surgical approach in children with thyroid cancer.

Main Methods:

  • A retrospective review of medical records was conducted for 68 pediatric patients (<19 years) who underwent surgical resection of a malignant thyroid nodule.
  • Data were collected from two academic institutions between 1962 and 2008.

Main Results:

  • Total thyroidectomy was performed in 74% (50/68) of pediatric patients.
  • Minor complications occurred in 21% of surgeries, with temporary hypocalcemia in 19%.
  • Patients undergoing lobectomy or subtotal thyroidectomy had a higher risk (21%) of requiring a second surgical procedure compared to total thyroidectomy.

Conclusions:

  • The type of surgery did not significantly impact the risk of surgical complications in pediatric thyroid cancer.
  • Less than total thyroidectomy was associated with an increased risk of repeat surgery.
  • Total thyroidectomy is recommended as the standard of care for managing pediatric thyroid cancer due to lower reoperation rates.
Abstract

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