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Updated: Jun 21, 2026

A Mouse Ear Model for Allergic Contact Dermatitis Evaluation
Published on: March 24, 2023
Hand dermatitis: a focus on allergic contact dermatitis to biocides
Lisa E Maier1, Heather P Lampel, Tina Bhutani
1Department of Dermatology, University of Michigan, 1910 A. Taubman Center 0314, 1500 East Medical Center Drive, Ann Arbor, MI 48109-0314, USA. maierl@umich.edu
Biocides used as preservatives are common causes of allergic contact dermatitis, leading to hand dermatitis and reduced quality of life. This review covers prevalent biocides responsible for hand dermatitis.
Area of Science:
- Dermatology
- Allergology
- Toxicology
Background:
- Hand dermatitis significantly impairs quality of life.
- Allergic contact dermatitis is a primary cause of hand dermatitis.
- Biocides in preservatives are increasingly identified as hand allergens.
Purpose of the Study:
- To review common biocides implicated in hand dermatitis.
- To inform clinicians and researchers about biocides causing allergic contact hand dermatitis.
Main Methods:
- Literature review of studies on biocides and hand dermatitis.
- Analysis of reported cases of allergic contact dermatitis linked to biocides.
Main Results:
- Several biocides commonly used as preservatives are identified as frequent allergens.
- These biocides contribute significantly to the burden of hand dermatitis.
Conclusions:
- Awareness of biocidal allergens is crucial for managing hand dermatitis.
- Identifying and avoiding specific biocides can improve patient outcomes.
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