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Published on: February 4, 2021
[Valvular heart disease associated with coronary artery disease]
1Başkent Universitesi Tip Fakültesi, Kardiyoloji Anabilim Dali, Ankara, Türkiye. ayliny@baskent-ank.edu.tr
Insights
Age-related heart valve disease, particularly aortic stenosis and ischemic mitral regurgitation, increasingly co-occurs with coronary artery disease. Management strategies focus on valve repair or replacement during bypass surgery for improved patient prognosis.
Area of Science:
- Cardiology
- Cardiac Surgery
- Geriatric Medicine
Context:
- Age-related degenerative etiologies are now the primary cause of valvular heart disease, surpassing rheumatic causes.
- Coronary artery disease (CAD) is increasingly associated with valvular heart disease, especially degenerative aortic valve disease, which shares similarities with atherosclerosis.
- The co-occurrence of CAD and valvular heart disease necessitates a review of current therapeutic approaches.
Purpose:
- To discuss the main characteristics of patients presenting with concomitant coronary artery disease and valvular heart disease.
- To outline therapeutic options for valvular heart disease in the context of coronary artery disease, considering individual valve pathologies.
- To highlight the significance of ischemic mitral regurgitation in patients with CAD.
Summary:
- Degenerative aortic valve disease is the leading valvular pathology associated with CAD.
- Severe aortic stenosis typically requires aortic valve replacement during coronary bypass surgery.
- For ischemic mitral regurgitation, mitral valve repair is preferred over replacement during coronary bypass surgery, especially in severe cases. Moderate cases also often warrant surgical intervention alongside CAD treatment.
Impact:
- Provides a comprehensive overview of managing patients with combined coronary and valvular heart disease.
- Emphasizes the importance of addressing valvular pathology during coronary artery bypass surgery for improved patient outcomes.
- Guides clinical decision-making for moderate and severe aortic stenosis and ischemic mitral regurgitation in the setting of CAD.
Abstract:
Nowadays, age-related degenerative etiologies have largely replaced the rheumatic ones and as a natural result of this etiologic change, coronary artery disease has become associated with valvular heart disease to a greater extent. Degenerative aortic valve disease has an important pathophysiological similarity to atherosclerosis and is the leader in this association. There is a general consensus that severely stenotic aortic valve should be replaced during bypass surgery for severe coronary artery disease. For moderate degree aortic stenosis, aortic valve replacement is usually performed during coronary bypass surgery. Ischemic mitral regurgitation has recently received great attention from both diagnostic and therapeutic points of view. Ischemic mitral regurgitation significantly alters the prognosis of the patient with coronary artery disease. Severe ischemic mitral regurgitation should be corrected during coronary bypass surgery and mitral valve repair should be preferred to valve replacement. For moderate degree ischemic mitral regurgitation, many authors prefer valve surgery with coronary bypass surgery. In this review, the main characteristics of patients with coronary artery disease accompanying valvular heart disease and the therapeutic options based on individual valve pathology are discussed.
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