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Single-Molecule Fluorescence Visualization of DNA Polymerase Dynamics at G-Quadruplexes
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Stability of intramolecular quadruplexes: sequence effects in the central loop.

Aurore Guédin1, Patrizia Alberti, Jean-Louis Mergny

  • 1INSERM, U565, Acides Nucléiques, Dynamique, Ciblage et Fonctions Biologiques, Paris Cedex 05 F-75231, France.

Nucleic Acids Research
|July 8, 2009
PubMed
Summary

Understanding quadruplex DNA stability is key. Adenine at the first loop position significantly reduces stability, while its position elsewhere has no negative impact. Cytosine

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