Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

A digital three-dimensional atlas of structure/function relationships.

A W Toga1

  • 1Department of Neurology, UCLA School of Medicine 90024.

Journal of Chemical Neuroanatomy
|September 1, 1991
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Editorial: How Will Aducanumab Approval Impact AD Research?

The journal of prevention of Alzheimer's disease·2021
Same author

Signal Hyperintensity on Unenhanced T1-Weighted Brain and Cervical Spinal Cord MR Images after Multiple Doses of Linear Gadolinium-Based Contrast Agent.

AJNR. American journal of neuroradiology·2019
Same author

Connectome imaging for mapping human brain pathways.

Molecular psychiatry·2017
Same author

Toward Precision and Reproducibility of Diffusion Tensor Imaging: A Multicenter Diffusion Phantom and Traveling Volunteer Study.

AJNR. American journal of neuroradiology·2016
Same author

Hot Topics in Research: Preventive Neuroradiology in Brain Aging and Cognitive Decline.

AJNR. American journal of neuroradiology·2015
Same author

FASTKD2 is associated with memory and hippocampal structure in older adults.

Molecular psychiatry·2014
Same journal

Brain Mechanisms - An evolving perspective on the future of neuroscience.

Journal of chemical neuroanatomy·2024
Same journal

Lymphatic Vessels Accompanying Dorsal and Basal Dural Sinuses in the Human Brain.

Journal of chemical neuroanatomy·2024
Same journal

Retraction notice to "Astrocyte response to melatonin treatment in rats under high-carbohydrate high-fat diet" [J. Chem. Neuroanat. 136 (2024) 102389].

Journal of chemical neuroanatomy·2024
Same journal

Retraction notice to "Aqueous leaf extract of Phyllanthus amarus protects against oxidative stress and misfiring of dopaminergic neurons in Paraquat-induced Parkinson's disease-like model of adult Wistar rats" [J. Chem. Neuroanat. 135 (2024) 102365].

Journal of chemical neuroanatomy·2024
Same journal

Retraction notice to "Coenzyme Q10 attenuates neurodegeneration in the cerebellum induced by chronic exposure to tramadol" [J. Chem. Neuroanat. 135 (2024) 102367].

Journal of chemical neuroanatomy·2024
Same journal

Retraction notice to "Maternal diabetes-induced alterations in the expression of brain-derived neurotrophic factor in the developing rat hippocampus" [J. Chem. Neuroanat. 114(2021) 101946].

Journal of chemical neuroanatomy·2024
See all related articles

Researchers developed methods for a digital 3D brain atlas, integrating anatomical and physiological data from serial sections. This interactive atlas aims to quantitatively describe brain structure and function.

Area of Science:

  • Neuroscience
  • Medical Imaging
  • Computational Biology

Background:

  • Developing comprehensive digital brain atlases is crucial for understanding complex neural structures and functions.
  • Existing atlases often lack the integration of both anatomical and physiological data in a quantitative, interactive format.

Purpose of the Study:

  • To discuss the techniques and challenges in creating a digital three-dimensional (3D) atlas of brain structure and function.
  • To establish methods for an interactive and quantitative stereotactic atlas.
  • To integrate anatomical and physiological data for a comprehensive brain map.

Main Methods:

  • Utilized serial sections for data acquisition.
  • Incorporated unstained tissue sections.
  • Employed thionein staining for anatomical detail.

Related Experiment Videos

  • Integrated 2-deoxyglucose autoradiographic data for physiological information.

    • Main Results:

    • Demonstrated the feasibility of creating a digital 3D brain atlas.
    • Showcased methods for quantitative stereotactic analysis.
    • Integrated diverse datasets (anatomical and physiological) into a unified framework.

    Conclusions:

    • The development of interactive, quantitative digital brain atlases is achievable.
    • Integrating anatomical and physiological data enhances the utility of brain atlases.
    • This approach provides a foundation for advanced neuroscience research and clinical applications.