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A Neonatal Imaging Model of Gram-Negative Bacterial Sepsis
Published on: August 12, 2020
Neonatal melioidosis: a case report from India
M J C Noyal1, B N Harish, V Bhat
1Department of Microbiology, Jawaharlal Institute of Post-Graduate Medical Education and Research (JIPMER), Pondicherry, India.
Abstract:
Melioidosis, caused by Burkholderia pseudomallei , is an infectious disease of major public health importance in Southeast Asia and Australia. We report, for the first time from the Indian subcontinent, a case of melioidosis in a neonate, its clinical presentation, microbiological diagnosis, possible mode of transmission and outcome. A pre-term female baby developed respiratory distress soon after birth. The child was febrile, had tachypnea, grunting, normal heart rate with a low pulse volume and poor peripheral perfusion. Chest X-ray revealed right-sided bronchopneumonia. B. pseudomallei was isolated from the blood culture of the neonate collected aseptically. The neonate was successfully treated with meropenem.
Insights
Melioidosis, a serious infectious disease caused by Burkholderia pseudomallei, was diagnosed in an Indian subcontinent neonate for the first time. The infant recovered after successful treatment with meropenem.
Area of Science:
- Infectious Diseases
- Microbiology
- Neonatal Care
Background:
- Melioidosis, caused by Burkholderia pseudomallei, is a significant public health concern in Southeast Asia and Australia.
- This report details the first documented case of melioidosis in a neonate from the Indian subcontinent.
Observation:
- A preterm neonate presented with respiratory distress, fever, tachypnea, and poor perfusion shortly after birth.
- Chest X-ray indicated right-sided bronchopneumonia.
- Burkholderia pseudomallei was identified from the neonate's blood culture.
Findings:
- The neonate was diagnosed with melioidosis, a rare condition in newborns from this region.
- The causative agent, Burkholderia pseudomallei, was successfully isolated and identified.
- The clinical presentation included severe respiratory compromise.
Implications:
- This case highlights the potential for melioidosis in neonates within the Indian subcontinent.
- Early diagnosis and appropriate antibiotic treatment, such as meropenem, are crucial for favorable outcomes.
- Further surveillance and awareness are needed to understand transmission and incidence in this geographical area.
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