Related Experiment Video
Updated: Jun 21, 2026

Preoxygenation Techniques for Tracheal Intubation in Critically Ill Adults Utilizing Oxygen Mask and Noninvasive Ventilation
Published on: December 5, 2025
Should patients be manually ventilated during rapid sequence induction of anaesthesia?
Paul Clements1, Stephen J Washington, Anthony McCluskey
1Department of Anesthesia, Stepping Hill Hospital, Stockport, UK.
Abstract:
Pulmonary aspiration of gastric contents has been recognized as a cause of significant morbidity and mortality during anaesthesia since the classic publication by Mendelson in 1946. The introduction of suxamethonium 5 years later allowed tracheal intubation to be achieved under complete muscle relaxation within 1 minute of induction of anaesthesia. In 1961 Sellick described the use of cricoid pressure to prevent gastric regurgitation.
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