Related Experiment Video
Updated: Jun 21, 2026

Cell-free Biochemical Fluorometric Enzymatic Assay for High-throughput Measurement of Lipid Peroxidation in High Density Lipoprotein
Published on: October 12, 2017
Oxidized LDL and paraoxanase status in ischemic stroke patients
Purnima Dey Sarkar1, Sushree S Rautaray
1Department of Biochemistry, M. G. M. Medical College, Indore.
Abstract:
Stroke is the leading cause of mortality and long term disability among adults in industrialized countries. Oxidative stress is an independent risk actor by inducing production of oxygen free radicals in ischemic stroke. Because a relationship may be associated between ox-ldl and paraoxanase, the aim of this study was to investigate the association between ox-ldl and paraoxanase in ischemic stroke patients by determining whether ox-ldl is a useful marker for monitoring oxidative stress in ischemic stroke patients. Our study included 100 patients of ischemic stroke and 100 controls. Compared with controls ox-ldl was significantly raised in stroke patients and Paraoxanase activity was low. Our findings suggest that there is a significant association between raised plasma ox-ldl and decrease activity of Paraoxanase with age indicating that plasma ox-ldl may reflect oxidative stress in ischemic stroke patients.
Related Concept Videos
Ischemic Stroke ll: Pathophysiology
Oxidation of Phenols to Quinones
o-hydroxy phenols are oxidized to o-quinones and p-hydroxy phenols to p-quinones. Such redox reactions involve the transfer of two electrons and two protons. The reversible redox property is crucial in...
Ischemic Stroke l: Introduction
Ischemic Heart Disease: Overview
Atherosclerosis, the primary malefactor, orchestrates this dangerous condition. It manifests as the accumulation of fatty deposits, akin to insidious plaques, within arterial walls. As time elapses, these plaques metamorphose, hardening and narrowing...
Atherosclerosis III: Management
