Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Related Concept Videos

Glaucoma: Overview

Glaucoma: Overview

Glaucoma is an eye condition characterized by increased intraocular pressure that damages the retina and optic nerve, leading to irreversible blindness if left untreated. The human eye has various components, including the cornea, iris, pupil, lens, and optic nerve. Aqueous humor is secreted by the epithelium of the ciliary body in the posterior chamber and flows through the trabecular meshwork and canal of Schlemm, maintaining normal intraocular pressure. The trabecular meshwork and the canal...

Open Angle Glaucoma: Treatment

Open Angle Glaucoma: Treatment

In open-angle glaucoma, the iridocorneal angle remains open, but the trabecular meshwork becomes stiff, slowing down the outflow of aqueous humor. This causes a buildup of aqueous humor in the anterior chamber, leading to a sudden increase in intraocular pressure. The treatment for open-angle glaucoma focuses on reducing the elevated intraocular pressure by either decreasing the secretion of aqueous humor or increasing its outflow.
Drugs such as carbonic anhydrase inhibitors, α2- and...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

Retinal Vasculitis in the Setting of <i>Mycobacterium tuberculosis</i> Exposure: Clinical Course and Management of Three Cases.

Case reports in ophthalmology·2025

Same author

Demarcation Laser Photocoagulation for Rhegmatogenous Retinal Detachment: Outcomes in Symptomatic and Asymptomatic Patients.

Case reports in ophthalmology·2025

Same author

Recurrent Intraocular Hemorrhage after Scleral Sutured Intraocular Lens.

Ophthalmology·2025

Same author

PERSISTENT MACULAR HOLE AND CYSTOID MACULAR EDEMA TREATED WITH PARS PLANA VITRECTOMY AFTER FAILURE WITH TOPICAL THERAPY.

Retinal cases & brief reports·2025

Same author

Prevalence of HSV Genomic Signatures Among Acanthamoeba Hosts and Contaminated Lens Cases: A Molecular and Clinical Study.

Investigative ophthalmology & visual science·2025

Same author

Tractional Retinoschisis in Proliferative Diabetic Retinopathy Imaged With Swept-Source Optical Coherence Tomography Angiography.

Ophthalmic surgery, lasers & imaging retina·2025

Search research articles

Related Experiment Video

Updated: Jun 21, 2026

Intravitreal Injection and Quantitation of Infection Parameters in a Mouse Model of Bacterial Endophthalmitis

Intravitreal Injection and Quantitation of Infection Parameters in a Mouse Model of Bacterial Endophthalmitis

Published on: February 6, 2021

Endophthalmitis after intravitreal injections.

Stephen G Schwartz¹, Harry W Flynn, Ingrid U Scott

¹University of Miami Miller School of Medicine, Bascom Palmer Eye Institute at Naples, Naples, FL 34102, USA. sschwartz2@med.miami.edu

Expert Opinion on Pharmacotherapy

|July 10, 2009

Summary

Endophthalmitis after intravitreal injections is rare but serious. Standardized injection protocols significantly reduce infection risk, crucial for differentiating infectious from noninfectious causes.

More Related Videos

Intracameral Injection in Rats with Low Risk of Adverse Effects

Intracameral Injection in Rats with Low Risk of Adverse Effects

Published on: May 31, 2024

Related Experiment Videos

Last Updated: Jun 21, 2026

Intravitreal Injection and Quantitation of Infection Parameters in a Mouse Model of Bacterial Endophthalmitis

Intravitreal Injection and Quantitation of Infection Parameters in a Mouse Model of Bacterial Endophthalmitis

Published on: February 6, 2021

Intracameral Injection in Rats with Low Risk of Adverse Effects

Intracameral Injection in Rats with Low Risk of Adverse Effects

Published on: May 31, 2024

Area of Science:

Ophthalmology
Infectious Diseases

Background:

Endophthalmitis is a rare but severe complication following intravitreal injections.
Distinguishing infectious endophthalmitis from noninfectious inflammation is clinically important.

Purpose of the Study:

To highlight the risks associated with intravitreal injections.
To emphasize the importance of standardized protocols in preventing endophthalmitis.

Main Methods:

Review of clinical data and literature on endophthalmitis post-intravitreal injection.
Analysis of risk factors and preventative measures.

Main Results:

The incidence of endophthalmitis following intravitreal injection is very low.
Standardized injection techniques are effective in minimizing infection risk.

Conclusions:

While infrequent, endophthalmitis is a significant concern after intravitreal procedures.
Adherence to standardized injection protocols is key to patient safety and reducing infectious complications.