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Published on: October 25, 2024
[Retro- and parapharyngeal infections: standardization of their management]
S Fédérici1, C Silva, C Maréchal
1Unité des urgences pédiatriques, hôpital des Enfants, Toulouse cedex 09, France.
Insights
Parenteral antibiotic therapy is the primary treatment for retropharyngeal and parapharyngeal infections in children over six months. Surgical drainage is reserved for cases not improving within 48-72 hours, based on clinical status and abscess accessibility.
Area of Science:
- Pediatric Infectious Diseases
- Otolaryngology
- Medical Imaging
Background:
- Retropharyngeal and parapharyngeal infections are serious pediatric conditions requiring prompt diagnosis and management.
- Management strategies have evolved, necessitating updated clinical guidelines.
Purpose of the Study:
- To analyze changes in the management of pediatric retropharyngeal and parapharyngeal infections.
- To propose a diagnostic and treatment algorithm for these infections.
Main Methods:
- Retrospective survey of children under 15 with these infections (2001-2005).
- Analysis of clinical, biological, and radiological data, including cervical computed tomographic (CT) scans.
- Correlation of surgical findings with CT scan results.
Main Results:
- Thirty-one patients were included; 93.5% underwent CT scans, identifying abscesses in 55.2%.
- Antibiotic therapy was standard; surgical drainage was performed in 93.5% initially but decreased by a factor of 3 in the latter study period.
- No significant difference in outcomes (treatment duration, hospitalization) was found between antibiotic-only and antibiotic plus surgical drainage groups.
Conclusions:
- Parenteral antibiotic therapy is recommended as first-line for children over 6 months without severe sepsis.
- CT scan is indicated for non-improving cases to assess infection extent and complications.
- Surgical drainage decisions should be based on clinical status and abscess accessibility.
Aim:
To analyze the changes in the management of retropharyngeal and parapharyngeal infections and propose a decisional algorithm for their diagnosis and treatment.
Patients And Methods:
A retrospective survey was carried out in a tertiary care pediatric hospital between January 2001 and December 2005. All children aged less than 15 years and affected by a retro- or parapharyngeal infection were included. Clinical, biological, and radiological data, medical and surgical treatment, and complications were extracted from the review of medical charts. The results of the surgical findings were correlated with a cervical computed tomographic scan (CT scan).
Results:
Thirty-one patients were included, 64.5% during the last 2 years of the study period. All children presented fever and a stiff neck. The pharyngeal examination revealed a retropharyngeal bulge in a quarter of the population and an upper respiratory tract infection was concomitant in 68% of cases. A CT scan was carried out in 29 of 31 children (93.5%), with the radiological diagnosis of an abscess in 16 children (55.2%), presuppurative adenitis in 8 children (27.6%), and cellulitis in 5 children (17.2%). The CT scan was performed within 0.75 days of admission in 2001 and 2.3 days in 2005. All children were treated with intravenous antibiotic therapy: an association of amoxicillin/clavulanic acid and an aminoglycoside in most cases. The mean duration of intravenous antibiotic therapy was 5.2 days. Seventeen patients (93.5%) underwent surgical drainage and purulent material was found in 82.3% of cases. The accuracy of the CT scan, confirmed by surgical finding of a purulent material, was 71.4% in correctly identifying an abscess. The mean duration of surgical treatment after admission increased from 1.7 days in 2001 to 3.3 days in 2005. The number of patients who underwent surgery was divided by a factor of 3 in the second period of the study. Two groups were compared: group A (n=12) treated with antibiotic therapy and group B (n=17) treated with antibiotics and surgical drainage. No significant difference was found between the two groups considering the duration of parenteral and oral antibiotic therapy, the standardization of cervical mobility, the mean time for apyrexia, and the length of hospitalization. There was one recurrence in group B 1 month later, and one case of sepsis in group A. None of the patients with retropharyngeal infection died.
Conclusion:
Without clinical evidence of severe sepsis, parenteral antibiotic therapy is recommended as the first-line treatment for children over 6 months of age presenting with retropharyngeal and parapharyngeal infections. If the clinical and/or biological conditions do not improve within 48-72h, a CT scan is indicated to assess the extent of infection and exclude complications. The decision to initiate surgical drainage depends on the patient's clinical status and the accessibility of the abscess.
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