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Synthesis and Purification of Iodoaziridines Involving Quantitative Selection of the Optimal Stationary Phase for Chromatography
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Controlling hazardous chemicals in microreactors: synthesis with iodine azide

Johan C Brandt1, Thomas Wirth

  • 1Cardiff University, School of Chemistry, Park Place, Cardiff CF10 3AT, UK.

Beilstein Journal of Organic Chemistry
|July 11, 2009
PubMed
Summary

Aromatic aldehydes can be safely converted to carbamoyl azides using iodine azide in microreactors. This continuous flow method offers a safer alternative for synthesizing these important chemical intermediates.

Keywords:
azideflow chemistryhazardous reagentsmicroreactorrearrangement

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