Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Related Concept Videos

Investigation of Disease Outbreaks

Investigation of Disease Outbreaks

Multistate foodborne outbreaks pose significant public health risks and require meticulous investigation to identify sources and implement control measures. The Centers for Disease Control and Prevention (CDC) utilizes a dynamic seven-step process for these investigations, integrating data from laboratories, interviews, and environmental assessments to protect public health.Outbreak Detection: The detection of multistate outbreaks typically begins with PulseNet, the CDC's national laboratory...

Statistical Software for Data Analysis and Clinical Trials

Statistical Software for Data Analysis and Clinical Trials

Statistical software is pivotal in data analysis and clinical trials by providing tools to analyze data, draw conclusions, and make predictions. These software packages range from simple data management applications to complex analytical platforms, supporting various statistical tests, models, and simulation techniques. Their significance lies in their ability to handle vast amounts of data with precision and efficiency, enabling researchers to validate hypotheses, identify trends, and make...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

New Upper Limit on the Axion-Photon Coupling with an Extended CAST Run with a Xe-Based Micromegas Detector.

Physical review letters·2024

Same author

Interventions for Managing Late Gastrointestinal Symptoms Following Pelvic Radiotherapy: a Systematic Review and Meta-analysis.

Clinical oncology (Royal College of Radiologists (Great Britain))·2024

Same author

PFAS levels and determinants of variability in exposure in European teenagers - Results from the HBM4EU aligned studies (2014-2021).

International journal of hygiene and environmental health·2022

Same author

Search for Dark Matter Axions with CAST-CAPP.

Nature communications·2022

Same author

Structural characterization of aspartate-semialdehyde dehydrogenase from Pseudomonas aeruginosa and Neisseria gonorrhoeae.

Scientific reports·2022

Same author

A flare of pre-existing erythema multiforme following BNT162b2 (Pfizer-BioNTech) COVID-19 vaccine.

Clinical and experimental dermatology·2021

Same journal

Cross-System Transcriptomics Suggests Enterovirus A71 Exploits Wound Healing Programs to Target Neural Progenitors in Human Spinal Cord Organoids.

Infectious disorders drug targets·2026

Same journal

Harnessing the Power of Chinese Essential Oils: A Systematic Review on Holistic Approach to Acne Treatment and Anti-Aging Therapy.

Infectious disorders drug targets·2026

Same journal

Diagnosis of Skin Parasites, Bacteria, and Fungi and Their Impact on Hematological Parameters in Patients with T-LGL Leukemia.

Infectious disorders drug targets·2026

Same journal

The Effective Dosing Schedule of Sodium Bicarbonate for Improving pH in Patients with Metabolic Acidosis.

Infectious disorders drug targets·2026

Same journal

Field Cancerization of the Cervix and Vulva in a Young HIV-Positive Woman: Diagnostic Challenges in Multifocal HPV Disease - A Case Report and Literature Review.

Infectious disorders drug targets·2026

Same journal

A Randomized Clinical Trial Evaluating Antimicrobial Effectiveness of a New Licorice Oral Gel against Salivary Streptococcus mutans.

Infectious disorders drug targets·2026

See all related articles

Search research articles

Related Experiment Video

Updated: Jun 21, 2026

Multi-target Parallel Processing Approach for Gene-to-structure Determination of the Influenza Polymerase PB2 Subunit

Multi-target Parallel Processing Approach for Gene-to-structure Determination of the Influenza Polymerase PB2 Subunit

Published on: June 28, 2013

The Seattle Structural Genomics Center for Infectious Disease (SSGCID).

P J Myler¹, R Stacy, L Stewart

¹Seattle Biomedical Research Institute, 307 Westlake Ave N, Seattle, WA 98109-5219, USA. peter.myler@sbri.org

Infectious Disorders Drug Targets

|July 15, 2009

Summary

This summary is machine-generated.

The Seattle Structural Genomics Center for Infectious Disease (SSGCID) uses structural genomics to find drug targets for infectious diseases. They aim to determine 400 protein structures and make resources available for future research and drug discovery.

More Related Videos

G2-seq: A High Throughput Sequencing-based Technique for Identifying Late Replicating Regions of the Genome

G2-seq: A High Throughput Sequencing-based Technique for Identifying Late Replicating Regions of the Genome

Published on: March 22, 2018

Related Experiment Videos

Last Updated: Jun 21, 2026

Multi-target Parallel Processing Approach for Gene-to-structure Determination of the Influenza Polymerase PB2 Subunit

Multi-target Parallel Processing Approach for Gene-to-structure Determination of the Influenza Polymerase PB2 Subunit

Published on: June 28, 2013

G2-seq: A High Throughput Sequencing-based Technique for Identifying Late Replicating Regions of the Genome

G2-seq: A High Throughput Sequencing-based Technique for Identifying Late Replicating Regions of the Genome

Published on: March 22, 2018

Area of Science:

Microbiology
Structural Biology
Drug Discovery

Background:

The Seattle Structural Genomics Center for Infectious Disease (SSGCID) is a consortium funded by the National Institute of Allergy and Infectious Diseases (NIAID).
It focuses on applying structural genomics to identify drug targets for biodefense and emerging infectious diseases.

Purpose of the Study:

To determine approximately 400 protein structures over five years.
To pursue ligand-based drug-lead discovery for high-impact targets.
To review target selection processes, structure determination, and ligand screening methodologies.

Main Methods:

Pro-active engagement with infectious disease researchers and drug therapy communities.
Identification of essential enzymes, virulence factors, and vaccine candidates.
Application of structural genomics approaches and structure determination pipelines.
Ligand screening methodology for drug-lead discovery.

Main Results:

The SSGCID has established processes for target selection and structure determination.
Ligand-based drug-lead discovery campaigns are integrated for high-impact targets.
Resources and data are being made available to the scientific community.

Conclusions:

The SSGCID aims to provide essential groundwork for future research and drug discovery.
Collaboration and resource sharing are key to combating infectious diseases.
Structural genomics is a valuable approach for identifying and developing new therapeutics.