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The reciprocal risks of stroke and cognitive impairment in an elderly population

Ya-Ping Jin1, Silvia Di Legge, Truls Ostbye

  • 1Department of Clinical Neurological Sciences, London Health Sciences Centre and University of Western Ontario, London, Ontario, Canada.

Alzheimer'S & Dementia : the Journal of the Alzheimer'S Association
|July 15, 2009
PubMed

Insights

Stroke and cognitive impairment significantly impact the elderly, with cognitive impairment no dementia (CIND) being highly prevalent. These conditions pose risks for each other, highlighting the need for further research.

Area of Science:

  • Geriatrics
  • Neurology
  • Epidemiology

Background:

  • Stroke, dementia, and cognitive impairment no dementia (CIND) are significant health concerns for the elderly.
  • These conditions have rarely been studied concurrently within the same population.
  • Understanding their interrelationship is crucial for effective public health strategies.

Purpose of the Study:

  • To compare the prevalence of stroke, CIND, and dementia in an elderly population.
  • To investigate the bidirectional relationship between cognitive impairment and stroke risk.

Main Methods:

  • Prevalence and incidence of stroke, CIND, and dementia were estimated using data from the Canadian Study of Health and Aging (CSHA).
  • Cox regression analyses were employed to assess the association between cognitive status and stroke risk.
  • The study included a large cohort of elderly Canadians (n=2,914 for baseline, n=828 for follow-up).

Main Results:

  • The age-standardized prevalence rates were 8% for stroke, 17% for CIND, and 8% for dementia.
  • Cognitive impairment was significantly more common in stroke survivors (64%) than in stroke-free individuals (21%).
  • Individuals with dementia had a 2.3 times higher adjusted risk for incident stroke compared to cognitively normal subjects.

Conclusions:

  • Stroke and cognitive impairment are mutually predictive, posing risks to each other.
  • Cognitive impairment no dementia (CIND) is highly prevalent and may indicate treatable conditions preceding stroke or dementia.
  • Early identification and intervention for CIND subtypes could mitigate risks for stroke and dementia.
Abstract

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