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Updated: Jun 21, 2026
08:12
Fully Endoscopic Mitral Valve Repair with Percutaneous Cannulation of Groin Vessels
Published on: May 26, 2023
Mitral valve repair for 52 patients with severe left ventricular dysfunction
Mikiko Murakami1, Hiroki Yamaguchi, Yuji Suda
1Department of Cardiovascular Surgery, Shin-Tokyo Hospital, Matsudo, Chiba, Japan.
Summary
Mitral valve repair is effective for patients with severe mitral regurgitation and low ejection fraction (EF < 35%). This procedure improved long-term survival and heart function in high-risk individuals.
Area of Science:
- Cardiovascular Surgery
- Cardiac Valve Repair
- Heart Failure Management
Background:
- Mitral valve (MV) repair generally offers better outcomes than replacement.
- MV repair in patients with severe left ventricular (LV) dysfunction carries higher mortality risks.
- Surgical indications for MV repair in patients with low LV ejection fraction (LVEF) remain debated.
Purpose of the Study:
- To evaluate the efficacy and safety of mitral valve repair in patients with severe mitral regurgitation and severe LV dysfunction (EF < 35%).
- To identify risk factors associated with mortality in this high-risk patient cohort.
Main Methods:
- A cohort of 52 patients with severe mitral regurgitation and severe LV dysfunction (EF < 35%) underwent MV repair.
- Etiology, procedures, pre- and perioperative parameters were analyzed.
- Follow-up data were collected for hospital survivors.
Main Results:
- Early mortality was 9.6%, primarily due to low cardiac output syndrome.
- Actuarial survival rates were 81.6% at 2 years and 76.5% at 5 years.
- Chronic hemodialysis and EF < 25% were identified as mortality risk factors. Survivors showed improved LVEF and reduced LV dimensions.
Conclusions:
- Mitral valve repair is a viable and effective treatment for high-risk patients with severe mitral regurgitation and severe LV dysfunction.
- The procedure leads to improved long-term prognosis and cardiac function in selected patients.
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