Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Blood vessel modeling.

L J Goldstein1, E B Rypins

  • 1Department of Surgery, University of California, Irvine Medical Center, Orange 92668.

International Journal of Bio-Medical Computing
|October 1, 1991
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Canadian Surgery Forum.

Canadian journal of surgery. Journal canadien de chirurgie·2022
Same author

An automated tube-type blood viscometer: validation studies.

Biorheology·2005
Same author

Docetaxel combined with trastuzumab is an active regimen in HER-2 3+ overexpressing and fluorescent in situ hybridization-positive metastatic breast cancer: a multi-institutional phase II trial.

Journal of clinical oncology : official journal of the American Society of Clinical Oncology·2004
Same author

Economic analysis of conventional-dose chemotherapy compared with high-dose chemotherapy plus autologous hematopoietic stem-cell transplantation for metastatic breast cancer.

Bone marrow transplantation·2003
Same author

Response time of the Opti-Q continuous cardiac output pulmonary artery catheter in the urgent mode to a step change in cardiac output.

Journal of clinical monitoring and computing·2003
Same author

Operable breast cancer.

Current treatment options in oncology·2002

This study presents a computer program to calculate hemodynamic parameters using Poiseuille's Law. The tool models vessel changes and simulates atherosclerosis, aiding in the analysis of vascular conditions.

Area of Science:

  • Biomedical Engineering
  • Computational Fluid Dynamics
  • Medical Physics

Background:

  • Hemodynamic analysis is crucial for understanding vascular diseases.
  • Accurate modeling of blood flow aids in diagnosing and treating conditions like atherosclerosis, stenosis, and aneurysms.
  • Existing methods may lack the interactive flexibility for dynamic vascular simulations.

Purpose of the Study:

  • To develop and present a computational tool for calculating hemodynamic parameters in vascular segments.
  • To enable interactive modeling of vascular pathologies such as stenoses and aneurysms.
  • To simulate hemodynamics in conditions like atherosclerosis and coarctation of the aorta.

Main Methods:

  • Utilized Poiseuille's Law for hemodynamic calculations.

Related Experiment Videos

  • Developed a computer program allowing user-defined vessel segment properties (viscosity, density, radius, length).
  • Incorporated interactive features for dilation/constriction to model vascular changes and input from angiographic data.

    • Main Results:

    • The program calculates key hemodynamic parameters: flow, pressure, flow velocity, fluid volume, pulse pressure, resistance, and Reynolds number.
    • Interactive graphical display of results for immediate analysis and printing.
    • Capability to estimate vascular resistance, flow velocity in diseased arteries, and predict laminar flow likelihood.

    Conclusions:

    • The developed program provides a flexible platform for hemodynamic analysis in vascular segments.
    • It facilitates the simulation of various vascular conditions, including atherosclerotic vessels, stenoses, aneurysms, and coarctation.
    • This tool aids in understanding blood flow dynamics and estimating risks associated with vascular abnormalities.