Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Pinching-off of Coated Vesicles01:32

Pinching-off of Coated Vesicles

Vesicle budding is orchestrated by distinct cytosolic proteins such as adaptor proteins, coat proteins, and GTPases. To initiate vesicle budding, membrane-bending proteins containing crescent-shaped BAR domains bind to the lipid heads in the bilayer and distort the membrane to form a protein-coated vesicle bud. Adaptors proteins such as AP2 for clathrin-coated vesicles can nucleate on the deformed membrane. Finally, coat proteins such as clathrin or COPI and COPII assemble into a coat forming...
Mechanism of Filopodia Formation01:39

Mechanism of Filopodia Formation

Filopodia are thin, actin-rich cellular protrusions that play an important role in many fundamental cellular functions. They vary in their occurrence, length, and positioning in different cell types, suggesting their diverse roles.
Their main function is to guide migrating cells during normal tissue morphogenesis or cancer metastasis by recognizing and making initial contacts with the extracellular matrix. However, they can also act as stationary cell anchors or help to establish communication...
Generation of Straight or Branched Actin Filaments01:14

Generation of Straight or Branched Actin Filaments

The straight or branched structure formation of actin filaments is controlled by nucleating proteins such as the formins and Arp2/3 complex. Formin-mediated assembly results in straight filaments, whereas Arp2/3 protein complex-mediated assembly results in branched actin filaments.
Arp2/3 Complex
Arp2/3 complex is a seven-subunit complex consisting of two proteins similar to actin- Arp2 and Arp3, and five other subunits that help keep Arp2 and Arp3 inactive. When required, the complex is...
Anchoring Junctions01:03

Anchoring Junctions

Anchoring junctions are multiprotein complexes that help cells connect to other cells and the extracellular matrix. Anchoring junctions are present on the lateral and basal surfaces of cells, providing strong and flexible connections. Focal adhesions are often formed due to cell interactions with the ECM substrata, which initiate signal transduction via kinase cascades and other mechanisms. Together, they provide stability and tissue integrity. There are three types of anchoring junctions:...
Mechanism of Lamellipodia Formation01:31

Mechanism of Lamellipodia Formation

Cells migrating in response to external stimuli form lamellipodia, which are thin membrane protrusions supported by a mesh of linked, branched, or unbranched actin filaments. These actin filaments interact with myosin motor proteins, creating the dynamic actomyosin complex within the cytoskeleton. Contractility, or the ability to generate contractile stress, is inherent to the actomyosin complex. It helps cells detect the stiffness of the surrounding ECM and exert contractile force for...
Actin Filament Depolymerization01:19

Actin Filament Depolymerization

Actin filaments (F-actin) are composed of actin subunits. The dissociation of actin monomers can occur from either end of F-actin. The rate of dissociation is faster from the minus-end or the pointed end, where the actin subunits exist with a bound ADP, together known as ADP-actin. The depolymerization of F-actin is aided by proteins, including the actin-depolymerizing factor (ADF) and cofilin family of proteins, gelsolin, and glia maturation factor (GMF).
In F-actin, the ADF/cofilin proteins...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Interlaboratory Comparison of a Glucagon and Oxyntomodulin Immuno-LC-MS/MS Assay: Implications for Diabetes Research.

Clinical chemistry·2026
Same author

Spontaneous Isomerization of Tau is Most Prevalent in Alzheimer's Disease.

NeuroMarkers·2026
Same author

Revisiting resonance-excitation collision-induced dissociation for data-independent acquisition.

bioRxiv : the preprint server for biology·2026
Same author

ToxBase: A Multidimensional ToxCast Reference Database for High-Throughput Human Exposome Analysis.

Environmental science & technology·2026
Same author

Prioritizing peptides for targeted mass spectrometry experiments using deep learning.

bioRxiv : the preprint server for biology·2026
Same author

A quantitative proteomics dataset for assessment and prediction of low dose X-ray radiation exposure in mice.

bioRxiv : the preprint server for biology·2026
Same journal

Developmental Modularity and Pre-Eclosion Sclerotization of the Pronotum Facilitate Eclosion in the Ladybird Beetle, Harmonia axyridis.

Evolution & development·2026
Same journal

Non-Invaginated Wing Primordia in Holometabolous Insects: First Report From Mecoptera.

Evolution & development·2026
Same journal

An Amelogenin Herbivore Motif, a Compacted Enamel Protein Matrix and Prismatic Enamel in Uromastyx Demonstrate Convergent Evolution in an Agamid Masticatory Apparatus.

Evolution & development·2026
Same journal

Exploring the Developmental Origins of Limb Proportion Diversity in Birds: An Analysis of Ontogenetic Timing.

Evolution & development·2026
Same journal

Correction to "The Development of De Villiers' Moss Frog (Arthroleptella villiersi, Pyxicephalidae) Reveals Heterochronic Patterns Underlying the Evolution of Endotrophic Development in Anura".

Evolution & development·2026
Same journal

Complex Wnt-Based Patterning of the Body Plan in the Colonial Hydrozoan Dynamena pumila (Linnaeus, 1758).

Evolution & development·2026
See all related articles

Related Experiment Video

Updated: Jun 21, 2026

Inducing Complete Polyp Regeneration from the Aboral Physa of the Starlet Sea Anemone Nematostella vectensis
08:17

Inducing Complete Polyp Regeneration from the Aboral Physa of the Starlet Sea Anemone Nematostella vectensis

Published on: January 14, 2017

Bindin from a sea star.

Susana Patiño1, Jan E Aagaard, Michael J MacCoss

  • 1Department of Biological Sciences, Simon Fraser University, Burnaby, BC, Canada V5A 1S6.

Evolution & Development
|July 16, 2009
PubMed
Summary
This summary is machine-generated.

Bindin, a key protein in sea urchin reproduction, is also found in sea stars. This discovery expands our understanding of bindin evolution and its role in speciation across echinoderms.

More Related Videos

The Barnacle Balanus improvisus as a Marine Model - Culturing and Gene Expression
07:47

The Barnacle Balanus improvisus as a Marine Model - Culturing and Gene Expression

Published on: August 8, 2018

Genotyping of Sea Anemone during Early Development
07:04

Genotyping of Sea Anemone during Early Development

Published on: May 13, 2019

Related Experiment Videos

Last Updated: Jun 21, 2026

Inducing Complete Polyp Regeneration from the Aboral Physa of the Starlet Sea Anemone Nematostella vectensis
08:17

Inducing Complete Polyp Regeneration from the Aboral Physa of the Starlet Sea Anemone Nematostella vectensis

Published on: January 14, 2017

The Barnacle Balanus improvisus as a Marine Model - Culturing and Gene Expression
07:47

The Barnacle Balanus improvisus as a Marine Model - Culturing and Gene Expression

Published on: August 8, 2018

Genotyping of Sea Anemone during Early Development
07:04

Genotyping of Sea Anemone during Early Development

Published on: May 13, 2019

Area of Science:

  • Evolutionary biology
  • Reproductive biology
  • Genetics

Background:

  • Sperm-egg proteins are crucial for reproductive evolution.
  • Bindin protein studies in sea urchins illuminate gamete compatibility and speciation.
  • Bindin was previously thought to be specific to sea urchins (Echinoidea).

Purpose of the Study:

  • To characterize the bindin gene in the sea star Patiria miniata.
  • To investigate the evolutionary history and molecular characteristics of bindin beyond sea urchins.

Main Methods:

  • Sequencing and analysis of the bindin cDNA and its intron in Patiria miniata.
  • Comparative analysis of Patiria miniata bindin with sea urchin bindin.

Main Results:

  • A full-length bindin cDNA and intron were identified in Patiria miniata.
  • Patiria miniata bindin is larger than sea urchin bindin but shares domain structure and sequence features.
  • The evolutionary history of bindin is extended to the early Paleozoic.

Conclusions:

  • Bindin is not exclusive to sea urchins, suggesting a broader role in echinoderm reproduction.
  • This finding opens new avenues for studying bindin's role in sexual selection, life history, and speciation in sea stars.
  • The molecular evolution of bindin is a significant factor in the diversification of echinoderms.