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Intravascular ultrasound imaging: a current perspective.
K M Coy1, G Maurer, R J Siegel
1Department of Cardiology, Cedars-Sinai Medical Center, Los Angeles, California 90048.
Journal of the American College of Cardiology
|December 1, 1991
Summary
Intravascular ultrasound (IVUS) is an FDA-approved imaging tool for assessing vascular disease. While promising for endovascular interventions, its clinical utility and limitations require further definition.
Area of Science:
- Medical Imaging
- Cardiovascular Technology
- Interventional Cardiology
Background:
- Catheter-based intravascular ultrasound (IVUS) has transitioned from a research tool to an FDA-approved device.
- Currently used as an adjunct to contrast angiography in peripheral and coronary circulation.
- Clinical indications and utility for IVUS are still being established.
Purpose of the Study:
- To review the development of intravascular ultrasound technology.
- To highlight studies validating IVUS findings against histopathology.
- To discuss the potential of IVUS in improving endovascular interventions.
Main Methods:
- Review of in vitro validation studies and human subject applications of IVUS.
- Emphasis on studies comparing IVUS findings with histopathological results.
- Discussion of current applications and future directions for IVUS.
Main Results:
- IVUS demonstrates capabilities for qualitative and quantitative assessment of atherosclerotic vascular disease.
- Validation studies confirm the accuracy of IVUS in assessing vascular structures.
- Limitations include image quality degradation in severely diseased or calcified vessels.
Conclusions:
- Intravascular ultrasound holds significant promise for enhancing the assessment of vascular disease and guiding endovascular interventions.
- Further research is needed to fully define its clinical utility and overcome existing limitations.
- Future applications may include intracardiac imaging, pulmonary circulation assessment, and integration with computer image analysis.