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Updated: Jun 21, 2026

Immunohistochemical Analysis in the Rat Central Nervous System and Peripheral Lymph Node Tissue Sections
Published on: November 14, 2016
The distribution of enkephalin-immunoreactive cell bodies in the rat central nervous system
T Hökfelt1, R Elde, O Johansson
1Department of Histology, Karolinska Institute, Stockholm, Department of Medical Pharmacology, Uppsala University, Uppsala (Sweden) and Wyeth Laboratories, Philadelphia, Pa. U.S.A.
Abstract:
With the indirect immunofluorescence technique the distribution of methionine-enkephalin-immunoreactive cell bodies was studied in the central nervous system of rats pretreated with colchicine. The antiserum used did cross-react to 10% with leucine-enkephalin but to less than 0.1% with alpha-, beta-, and gamma-endorphine. Cell bodies with a specific immunofluorescence were observed in the tel-, di-, mes- and rhombencephalon and in the spinal cord.

