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Updated: Jun 21, 2026

High-resolution Functional Magnetic Resonance Imaging Methods for Human Midbrain
Published on: May 10, 2012
Evidence for branched subthalamic nucleus projections to substantia nigra, entopeduncular nucleus and globus pallidus
J M Deniau1, C Hammond, G Chevalier
1Laboratoire de Physiologie des centres nerveux, Universite Pierre et Marie Curie, 4, Place Jussieu 75230 Paris Cedex 05 France.
Abstract:
The organization of subthalamic (STN) projections to the substantia nigra (SN), entopeduncular nucleus (EN) and globus pallidus (GP) were studied in the rat. The neurons projecting from the STN were identified by antidromic activation from the target nuclei. Most of the STN cells projecting to EN and/or GP were found to send an axonal branch to the SN. The existence of such branched neurons suggest that STN output neurons might be of only one type and influence SN, EN and GP synchronously.
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