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Related Experiment Video

Updated: Jun 21, 2026

Behavioral Phenotyping of Murine Disease Models with the Integrated Behavioral Station (INBEST)
12:18

Behavioral Phenotyping of Murine Disease Models with the Integrated Behavioral Station (INBEST)

Published on: April 23, 2015

A data-capture tool for mouse pathology phenotyping.

B A Sundberg1, P N Schofield, M Gruenberger

  • 1The Jackson Laboratory, Bar Harbor, ME 04609-1500, USA.

Veterinary Pathology
|July 17, 2009
PubMed
Summary
This summary is machine-generated.

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The Mouse Disease Information System aids veterinary pathologists with data management and analysis. It uses ontologies for controlled vocabulary and quantitative scores for large-scale genetic studies.

Area of Science:

  • Veterinary Pathology
  • Bioinformatics
  • Comparative Pathology

Background:

  • Veterinary pathology requires efficient data acquisition and analysis for disease studies.
  • Managing tissue sample archives and diagnostic data presents significant challenges.

Purpose of the Study:

  • To introduce the Mouse Disease Information System, a free Microsoft Access database.
  • To enhance data standardization and quantitative analysis in mouse pathology research.

Main Methods:

  • Developed a Microsoft Access database for veterinary pathologists.
  • Integrated Mouse Anatomy and Mouse Pathology Ontologies for controlled vocabulary.
  • Incorporated severity scores for quantitative lesion assessment.
  • Linked to Pathbase.net for diagnosis verification and histologic image access.

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Mouse Eye Enucleation for Remote High-throughput Phenotyping
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Mouse Eye Enucleation for Remote High-throughput Phenotyping

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DNA-barcode-based Multiplex Immunofluorescence Imaging to Analyze FFPE Specimens from Genetically Reprogrammed Murine Melanoma
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DNA-barcode-based Multiplex Immunofluorescence Imaging to Analyze FFPE Specimens from Genetically Reprogrammed Murine Melanoma

Published on: June 6, 2025

Related Experiment Videos

Last Updated: Jun 21, 2026

Behavioral Phenotyping of Murine Disease Models with the Integrated Behavioral Station (INBEST)
12:18

Behavioral Phenotyping of Murine Disease Models with the Integrated Behavioral Station (INBEST)

Published on: April 23, 2015

Mouse Eye Enucleation for Remote High-throughput Phenotyping
05:30

Mouse Eye Enucleation for Remote High-throughput Phenotyping

Published on: November 19, 2011

DNA-barcode-based Multiplex Immunofluorescence Imaging to Analyze FFPE Specimens from Genetically Reprogrammed Murine Melanoma
09:58

DNA-barcode-based Multiplex Immunofluorescence Imaging to Analyze FFPE Specimens from Genetically Reprogrammed Murine Melanoma

Published on: June 6, 2025

Main Results:

  • Provides controlled vocabulary for organs, tissues, and diagnoses, ensuring consistency.
  • Enables quantitative trait locus analysis through lesion severity scoring.
  • Facilitates direct comparison of slides with online histologic images for "virtual second opinions".

Conclusions:

  • The Mouse Disease Information System streamlines data management for veterinary pathologists.
  • Ontology integration and quantitative scoring support advanced research, including genetic studies.
  • Online resources enhance diagnostic accuracy and provide valuable reference materials.