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Psychological stress and recurrent aphthous stomatitis
Camila de Barros Gallo1, Maria Angela Martins Mimura, Norberto Nobuo Sugaya
1Disciplina de Estomatologia Clínica, Departamento de Estomatologia, Faculdade de Odontologia, Universidade de São Paulo, São Paulo/SP, Brazil. camilagallo@gmail.com
Clinics (Sao Paulo, Brazil)
|July 17, 2009
Summary
Psychological stress may influence recurrent aphthous stomatitis (RAS) outbreaks. This study found higher stress levels in patients experiencing RAS compared to controls, suggesting stress acts as a trigger or modifier.
Area of Science:
- Oral medicine
- Psychoneuroimmunology
- Clinical psychology
Background:
- Recurrent aphthous stomatitis (RAS) is a common oral mucosal disease with unclear etiology.
- Potential contributing factors include hereditary, nutritional, infectious, and psychological elements.
Purpose of the Study:
- To investigate the association between psychological stress and the occurrence of recurrent aphthous stomatitis (RAS).
Main Methods:
- A case-control study involving 50 participants (25 RAS patients, 25 controls) matched for demographics.
- Stress assessment across emotional, physical, social, and cognitive domains using a 59-item validated questionnaire.
- Psychological evaluation by an expert psychologist.
Main Results:
- Patients with recurrent aphthous stomatitis (RAS) reported significantly higher levels of psychological stress compared to the control group (P < 0.05).
Conclusions:
- Psychological stress appears to be a potential trigger or modifying factor in the manifestation of recurrent aphthous stomatitis (RAS).
- Further research is warranted to elucidate the precise role of stress in RAS pathogenesis.
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