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Integration of Bioinformatics Approaches and Experimental Validations to Understand the Role of Notch Signaling in Ovarian Cancer
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Crosstalk of Notch with p53 and p63 in cancer growth control

G Paolo Dotto1

  • 1Department of Biochemistry, University of Lausanne, Epalinges CH-1066, Switzerland. gian-paolo.dotto@unil.ch.

Nature Reviews. Cancer
|July 18, 2009
PubMed

Insights

The Notch, p53, and p63 pathways interact dynamically in cancer, influencing stem cell potential and differentiation. Targeting these pathways offers a promising strategy to enhance cancer therapy efficacy and reduce side effects.

Area of Science:

  • Molecular biology
  • Cell signaling
  • Cancer research

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