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Comparison of procalcitonin measurement by a semi-quantitative method and an ultra-sensitive quantitative method in a
Sergio Manzano1, Benoit Bailey, Jean-Bernard Girodias
1Division of Emergency Medicine, CHU Sainte-Justine, Université de Montréal, Quebec, Canada.
Objective:
To compare procalcitonin measurements between semi-quantitative and quantitative assays.
Method:
Procalcitonin was measured with the PCT-Q and the Kryptor assays in a pediatric emergency department.
Results:
Among the 359 pairs of results, 103 had discordant results. The linear weighted kappa was 0.44 (95% CI 0.36, 0.51). The concordant/discordant results distribution varied depending on the laboratory technician (p=0.018).
Conclusion:
Agreement between procalcitonin measured semi-quantitatively and quantitatively was moderate. This is probably due to a subjective interpretation of the assay result.
