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Updated: Jun 21, 2026

Catheter Ablation in Combination With Left Atrial Appendage Closure for Atrial Fibrillation
Published on: February 26, 2013
Efficacy, safety and outcome of catheter ablation for atrial fibrillation in octogenarians
Insights
Catheter ablation for atrial fibrillation (AF) is safe and effective in octogenarians. Outcomes in patients aged 80 and over are comparable to younger individuals, with a lower need for repeat procedures.
Area of Science:
- Cardiology
- Electrophysiology
- Geriatric Medicine
Background:
- Atrial fibrillation (AF) is a common arrhythmia.
- Catheter ablation is an established treatment for AF.
- Octogenarians represent an understudied population for AF ablation.
Purpose of the Study:
- To assess the safety and efficacy of catheter ablation for AF in octogenarians.
- To compare outcomes in octogenarians versus younger patient groups.
Main Methods:
- Retrospective analysis of 377 consecutive AF patients undergoing catheter ablation.
- Patients stratified into three age groups: ≥80 (Group 1), 70-79 (Group 2), and 60-69 (Group 3).
- Efficacy, safety, and complication rates were evaluated over an 18-month follow-up.
Main Results:
- Similar success rates after one procedure across all age groups (70% in Group 1, 72% in Group 2, 74% in Group 3).
- Comparable major complication rates among the groups.
- Octogenarians had a lower likelihood of requiring repeat procedures (8%) compared to younger groups (15-18%).
Conclusions:
- Catheter ablation is a safe and effective treatment option for atrial fibrillation in octogenarians.
- Outcomes in octogenarians are comparable to those in younger patients, with added benefits of fewer repeat procedures.
Background And Objectives:
Catheter ablation is effective in treating patients with atrial fibrillation (AF). The aim of the study was to evaluate the safety, efficacy and outcome of catheter ablation for AF in octogenarians.
Methods And Results:
377 consecutive patients were divided into three groups based on age: ≥80 years (group 1; n=49), 70-79 years (group 2; n=151), 60-69 years (group 3; n=177). The efficacy and safety for those three groups were determined. The success rate after one procedure was similar in three groups (70% in group 1, 72% in group2 and 74% in group 3, P=NS) during a mean follow-up of 18 months. Major complication rates were comparable between the three groups. However, the octogenarians were less likely to undergo a repeated procedure than other groups (8% in group 1, 15% in group 2 and 18% in group 3, P<0.05), and were more likely to remain on antiarrhythmic drugs.
Conclusion:
Catheter ablation for AF attempted in octogenarians appears to be effective and with low risk. Ablation results are comparable with those noted in younger patients.
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