Related Experiment Video
Updated: Jun 21, 2026

08:23
Comet Assay as an Indirect Measure of Systemic Oxidative Stress
Published on: May 22, 2015
[Comet assay of DNA fragmentation: modification of silver staining for obtaining permanent preparations]
Ukrains'Kyi Biokhimichnyi Zhurnal (1999 )
|July 22, 2009
Abstract:
Modification of comet analysis is proposed for obtaining permanent preparations by DNA staining with silver compounds. The sensitivity of staining is similar to that observed at the treatment by ethidium bromide and other fluorochromes. The advantages of the method are stability of slides and possibility of their reinvestigation by light microscopy. The method does not need expensive fluorescent microscope and lacks contacting with carcinogenic compounds and UV light irradiation.

