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Preparation of Parasagittal Slices for the Investigation of Dorsal-ventral Organization of the Rodent Medial Entorhinal Cortex
Published on: March 28, 2012
The parietal association cortex of the rat
Fernando Torrealba1, José Luis Valdés
1Departamento de Fisiología, Facultad de Ciencias Biológicas, Pontificia Universidad Católica de Chile, Santiago, Chile. ftorrealba@bio.puc.cl
Biological Research
|July 22, 2009
Summary
This review explores the posterior parietal/anteromedial cortex and hippocampal formation
Area of Science:
- Neuroscience
- Cognitive Science
- Animal Behavior
Background:
- Spatial cognition is a complex mammalian function.
- It is crucial for various laboratory-explorable tasks.
- Understanding its neural basis is key.
Purpose of the Study:
- To review the roles of specific brain regions in spatial navigation.
- To highlight contributions to understanding behavioral functions.
- To focus on rodent models.
Main Methods:
- Literature review of studies on spatial cognition.
- Analysis of research on the parietal association cortex and hippocampal formation.
- Examination of behavioral studies related to spatial tasks.
Main Results:
- The posterior parietal/anteromedial cortex and hippocampal formation are critical for spatial navigation in rodents.
- These regions also support other higher-order associational functions.
- Dr. Pinto-Hamuy's work significantly advanced this understanding.
Conclusions:
- The parietal association cortex and hippocampus are central to mammalian spatial cognition.
- Further research in these areas can elucidate complex behavioral functions.
- Integrative approaches are vital for understanding neural mechanisms of cognition.
Related Concept Videos
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Association areas are regions of the cerebral cortex that do not have a specific sensory or motor function. Instead, they integrate and interpret information from various sources to enable higher cognitive processes such as memory, learning, and decision-making. Some key association areas include the following:
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The cerebral cortex, the brain's outermost layer, is pivotal in processing complex cognitive tasks, emotions, and various sensory inputs and executing voluntary motor activities. This intricate structure is divided into three primary functional areas: the motor areas, sensory areas, and association areas.
Motor Areas
The motor areas located in the frontal lobe are central to controlling voluntary movements. This region is further subdivided into the primary motor cortex and the premotor cortex.
Motor Areas
The motor areas located in the frontal lobe are central to controlling voluntary movements. This region is further subdivided into the primary motor cortex and the premotor cortex.
Lobes of the Cerebrum
The cerebral cortex, a critical structure of the brain, is intricately divided into two hemispheres, each consisting of four distinct lobes: occipital, temporal, frontal, and parietal. These lobes function cooperatively to regulate various cognitive and sensory functions, forming the basis of our complex neural capabilities.
Frontal lobe
The frontal lobes, located behind the forehead, are the command center of our brain, controlling personality, intelligence, and voluntary muscle movements.
Frontal lobe
The frontal lobes, located behind the forehead, are the command center of our brain, controlling personality, intelligence, and voluntary muscle movements.
Somatosensation
The somatosensory system relays sensory information from the skin, mucous membranes, limbs, and joints. Somatosensation is more familiarly known as the sense of touch. A typical somatosensory pathway includes three types of long neurons: primary, secondary, and tertiary. Primary neurons have cell bodies located near the spinal cord in groups of neurons called dorsal root ganglia. The sensory neurons of ganglia innervate designated areas of skin called dermatomes.
Functional Brain Systems: Reticular Formation
The reticular formation is a complex network of gray and white matter located within the brainstem extending from the medulla to the midbrain.
Within the reticular formation, there are several distinct nuclei that can be classified into three broad categories. The Raphe nuclei are located along the midline of the brainstem. They are primarily known for their role in synthesizing and releasing serotonin, a neurotransmitter involved in regulating mood, appetite, sleep, and circadian rhythms. The...
Within the reticular formation, there are several distinct nuclei that can be classified into three broad categories. The Raphe nuclei are located along the midline of the brainstem. They are primarily known for their role in synthesizing and releasing serotonin, a neurotransmitter involved in regulating mood, appetite, sleep, and circadian rhythms. The...

