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Updated: Jun 21, 2026

Drug-Induced Sleep Endoscopy (DISE) with Target Controlled Infusion (TCI) and Bispectral Analysis in Obstructive Sleep Apnea
Published on: December 6, 2016
Clinical practice: diagnosis and treatment of childhood snoring
Ioannis M Vlastos1, John K Hajiioannou
1Department of Otolaryngology, Aghia Sophia Children's Hospital of Athens, 26 Kirprion Agoniston, Dasos Haidariou, Athens, Greece. giannisvlastos@yahoo.gr
Insights
Pediatric obstructive sleep-disordered breathing ranges from simple snoring to severe obstructive sleep apnea. Current evidence suggests a multidisciplinary approach for diagnosis and treatment, moving beyond traditional adenotonsillectomy.
Area of Science:
- Pediatrics
- Sleep Medicine
- Otolaryngology
Background:
- Obstructive sleep-disordered breathing (OSDB) in children is common, with presentations varying from primary snoring to obstructive sleep apnea (OSA).
- OSA can lead to significant cognitive, cardiac, and growth issues in children.
- Inconsistent diagnostic methods hinder consensus on optimal treatment strategies.
Purpose of the Study:
- To review diagnostic modalities for pediatric OSDB.
- To evaluate current and alternative treatment options for pediatric OSDB.
- To propose an evidence-based diagnostic and treatment algorithm for pediatric OSDB.
Main Methods:
- Review of history, clinical examination, radiologic evaluations, and sleep studies.
- Analysis of various treatment modalities including adenotonsillectomy, continuous positive airway pressure (CPAP), and orthodontic interventions.
- Synthesis of evidence to propose a diagnostic and treatment workup.
Main Results:
- Adenotonsillectomy remains a primary treatment, but its limitations and recurrences are noted.
- Factors beyond adenotonsillar hypertrophy, such as obesity and craniofacial abnormalities, influence treatment outcomes.
- Multidisciplinary approaches involving various specialists are often necessary.
Conclusions:
- A comprehensive, multidisciplinary approach is essential for managing pediatric OSDB.
- Evidence-based diagnostic and treatment pathways are proposed.
- Individualized care plans are crucial for addressing the complexities of pediatric OSDB.
Abstract:
Obstructive sleep-disordered breathing in children is a relatively common problem, presenting in various ways, from primary snoring, without an apparent decrease in quality of life, to obstructive sleep apnea with cognitive, cardiac, and growth abnormalities. History, clinical examination, radiologic evaluations, sleep studies, and other diagnostic modalities are reviewed. Since application and interpretation of these methods are not consistent in studies of snoring, a consensus on optimal treatment options has not been established. Traditionally, adenotonsillectomy has long been the treatment of choice. Treatment failures or recurrences as well as the existence of causes and contributing factors other than adenotonsillar hypertrophy, like obesity, facial malformations, and Down syndrome, have changed the concept of adenotonsillectomy as the ultimate cure. Several other treatment options have been proposed on their own or in combination. Continuous positive airway pressure, anti-inflammatory medications, maxillofacial, and orthodontic treatments are reviewed suggesting the need of a multidisciplinary approach in some cases. Finally, at the end of the chapter, a diagnostic and treatment work up based on current evidence is proposed for otherwise normal children or children with specific conditions.
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