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Updated: Jun 21, 2026

Mizoroki-Heck Cross-coupling Reactions Catalyzed by Dichloro{bis[1,1',1''-(phosphinetriyl)tripiperidine]}palladium Under Mild Reaction Conditions
11:44

Mizoroki-Heck Cross-coupling Reactions Catalyzed by Dichloro{bis[1,1',1''-(phosphinetriyl)tripiperidine]}palladium Under Mild Reaction Conditions

Published on: March 20, 2014

COMU: a safer and more effective replacement for benzotriazole-based uronium coupling reagents

Ayman El-Faham1, Ramon Subirós Funosas, Rafel Prohens

  • 1Institute for Research in Biomedicine, Barcelona Science Park, Baldiri Reixac 10, 08028 Barcelona, Spain. aymanel_faham@hotmail.com

Chemistry (Weinheim an Der Bergstrasse, Germany)
|July 22, 2009
PubMed
Summary

Researchers developed new uronium coupling reagents, including COMU, which offers improved stability and a safer profile compared to older benzotriazole-based reagents. COMU demonstrates excellent performance in chemical reactions with reduced explosion risks.

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