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A novel HLA-DRB1 allele, DRB1*1219, was identified by sequence-based typing in a Chinese leukaemia family

X-M Nie1, Y-H Fang, Y Zhang

  • 1HLA Laboratory, Blood Center of Shandong Province, Shandong Province, China.

Tissue Antigens
|July 24, 2009
PubMed

A novel human leukocyte antigen DRB1 allele, DRB1*1219, has been identified in a Chinese leukaemia patient and his family by polymerase chain reaction sequence-based typing, which has one nucleotide change at position 341 (C-->T) in exon 2 from the closest matching allele DRB1*120201, resulting in an amino acid substitution from Ala-->Val at codon 85.

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