Primary suprasellar malignant tumor with odontogenic features: case report
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Published on: August 15, 2025
Hiroshi Nishioka1, Makoto Shibuya, Hitoshi Izawa
1Department of Neurosurgery, Hachioji Medical Center, Tokyo Medical University, Tokyo, Japan. nishioka@tokyo-med.ac.jp
Objective:
Primary malignant odontogenic tumors in the suprasellar region have rarely been reported.
Clinical Presentation:
A partially cystic tumor that originated from the stalk and showed rapid enlargement was observed in a 56-year-old woman.
Intervention:
Gross total removal of the tumor was performed with sacrifice of the stalk. The tumor was a malignant epithelial type with odontogenic features, whereas findings consistent with craniopharyngioma were absent. The tumor recurred 14 months after surgery.
Conclusion:
The present unusual tumor may represent a novel member of malignant tumors of the suprasellar region. Given the common embryological origin of craniopharyngiomas to odontogenic lesions, a possible correlation with craniopharyngioma was suggested.
