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Updated: Jun 21, 2026

Evaluation of Hemisphere Lateralization with Bilateral Local Field Potential Recording in Secondary Motor Cortex of Mice
Published on: July 31, 2019
Hemispheric lateralization of the corticostriatal glutamatergic system in the rat
Christine Capper-Loup1, Dominik Rebell, Alain Kaelin-Lang
1Department of Neurology and Department of Clinical Research, Inselspital, Bern University Hospital, University of Bern, Bern, Switzerland.
Abstract:
Little is known about hemispheric lateralization of subcortical structures. Here, we show a higher expression of the subunit NR2A of the NMDA receptor mRNA in the striatum and of vGluT1 mRNA in the cingulate cortex, in the left hemisphere compared to the right one. This suggests a lateralization of the glutamatergic cortico-subcortical system, at the level of postsynaptic receptors as well as at the level of corticostriatal projections. Such lateralization could play a role in asymmetric diseases like Parkinson's disease.
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Lateralization
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