Bilateral basal ganglionic lesions due to transdermal methanol intoxication

Area of Science:

• Toxicology
• Emergency Medicine
• Dermatology

Background:

• Methanol is a toxic alcohol found in common household products.
• Severe methanol intoxication typically results from oral ingestion.
• Transdermal methanol poisoning is a rare but serious condition.

Observation:

• A 47-year-old woman presented with symptoms of acute methanol intoxication.
• Her symptoms included weakness, blurred vision, and deteriorating consciousness.
• Physical examination revealed bilateral areactive mydriasis.

Findings:

• The patient's condition was diagnosed as acute transdermal methanol intoxication.
• This route of exposure is infrequently reported but can lead to severe toxicity.
• The case underscores the potential for significant systemic absorption through the skin.

Implications:

• Highlights the risk of methanol toxicity via non-oral routes.
• Emphasizes the need for vigilance in diagnosing transdermal poisoning.
• Suggests that skin exposure to methanol-containing products requires careful management.