[Pathogenesis of motor disorders in patients with vibration disease caused by local vibration...

The author provides the data on clinical, neurophysiological examinations of 195 patients suffering from vibration disease, stages I and II, due to local vibration. Three types of axonal injuries were established: axonal degeneration, demyelinization of the distal part of axon and demyelinization of its proximal part. All the three types of neural disorders were attended by synaptic alterations with a decrement of the M-response and the syndrome of "working in". The initial manifestations of neurophysiological pathology were axonal degenerative disorders with changes in neuromuscular transmission; on longer exposure to vibration there appeared the signs of demyelination. The length of service with vibrating tools is given fr the occupational groups with above-indicated neural disorders. The patterns of motor disorders did not depend on the type of vibrating tools, whereas the localization of the pathological alterations was related to the characteristic features of an industry.