[Clinico-electrophysiological changes in the neuromuscular system of patients with vibration disease]

Neuromuscular alterations associated with vibratory disease related to the pathology of spinal motoneurons, axon (degeneration, demyelinization), synapse, muscle. The site, nature and the intensity of the process depended on the duration of work with vibroinstruments, industrial characteristics. During specialized employment, the patients manifested aggravation of the clinical and neurophysiological parameters of the denervation process. Compensatory innervation of the muscles (branching of axon terminals, establishment of new neuromuscular contacts, ets.) was most effective in polishers and riveters. Foundry cleaners demonstrated a tendency toward progress of neuromuscular pathology. To explain motor disorders in patients with vibratory disease, the mechanisms of microtraumatization of nerve endings followed by involvement of the neurotrophic and neuroreflectory systems are suggested.