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Related Concept Videos

Enzyme-Linked Immunosorbent Assay01:33

Enzyme-Linked Immunosorbent Assay

In 1971, Peter Perlman and Eva Engvall developed an Enzyme-linked immunosorbent assay (ELISA or EIA). ELISA differs from western blot in that the assays are conducted in microtiter plates or in vivo rather than on an absorbent membrane.
There are many different types of ELISAs, but they all involve an antibody molecule whose constant region binds an enzyme, leaving the variable region free to bind its specific antigen.  Enzyme-substrate reaction allows the antigen to be visualized or quantified.

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Ultrasensitive Detection of Biomarkers by Using a Molecular Imprinting Based Capacitive Biosensor
08:22

Ultrasensitive Detection of Biomarkers by Using a Molecular Imprinting Based Capacitive Biosensor

Published on: February 16, 2018

Molecularly imprinted sorbent assays: recent developments and applications.

Yi Ge1, Anthony P F Turner

  • 1Cranfield Health, Vincent Building, Cranfield University, Cranfield, Bedfordshire, MK43 0AL UK. y.ge@cranfield.ac.uk

Chemistry (Weinheim an Der Bergstrasse, Germany)
|July 25, 2009
PubMed
Summary
This summary is machine-generated.

Molecular imprinting creates antibody-mimicking materials for specific binding. These molecularly imprinted sorbent assays offer stability, easy preparation, and low cost, with recent advances highlighted.

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Area of Science:

  • Analytical Chemistry
  • Materials Science
  • Biotechnology

Background:

  • Molecular imprinting offers specific recognition sites, mimicking antibodies.
  • Advantages include stability, ease of preparation, and cost-effectiveness.

Purpose of the Study:

  • To review recent progress in molecularly imprinted sorbent assays.
  • To highlight significant developments and applications in the field.

Main Methods:

  • Review of recent scientific literature on molecular imprinting.
  • Focus on sorbent assay methodologies and their applications.

Main Results:

  • Molecular imprinting provides robust, tailor-made recognition materials.
  • Recent advancements have expanded the scope and efficiency of imprinted sorbent assays.

Conclusions:

  • Molecularly imprinted sorbent assays are a promising technology.
  • Continued research is expected to yield further innovations and applications.