Related Experiment Video
Updated: Aug 12, 2026

3D Hydrogel Scaffolds for Articular Chondrocyte Culture and Cartilage Generation
Published on: October 7, 2015
[Proteoglycan and glycosaminoglycan from human femoral head cartilage]
Abstract:
The composition and the size of proteoglycans (PGs) and glycosaminoglycans (GAGs) from femoral head cartilage of different age were determined by caesium chloride density gradient centrifugation, sepharose chromatography and chemical analysis. The results showed that the size of PG subunits from articular cartilage decreases with increasing age. In PGs and GAGs from cartilage, uronic acid and galactosamine content decreased; the ratio of in keratin sulphate to chondroitin sulphate increased; glucosamine and hydroxyproline content decreased with age The cause of degenerative changes and the measures to prevent and treat them are discussed.
Related Concept Videos
Proteoglycans
Glycosaminoglycans
GAGS are found in the extracellular matrix of vertebrates, invertebrates, and bacteria. Due to their polar nature they attract water, and serve as excellent lubricants or shock absorbers in an animal body.
Hyaluronic...
Matrix Proteoglycans and Glycoproteins
Connective Tissue Fibers and Ground Substance
Knee Joint
A total of seven ligaments support the knee joint. The patellar ligament, which is also attached to the quadriceps femoris group...

