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A Customizable Approach for the Enzymatic Production and Purification of Diterpenoid Natural Products
Published on: October 4, 2019
Meroterpenoids produced by fungi
Regina Geris1, Thomas J Simpson
1Instituto de Química, Universidade Federal da Bahia, 40170-290 BA, Brasil. rmgeris@ufba.br
Natural Product Reports
|July 29, 2009
Summary
This review summarizes fungal meroterpenoids, natural products with mixed origins. It details their isolation, structure, biosynthesis, and biological activities, covering 333 compounds.
Area of Science:
- Natural Product Chemistry
- Mycology
- Biochemistry
Background:
- Meroterpenoids are fungal secondary metabolites with mixed biosynthetic origins.
- Fungi are prolific sources of diverse and complex natural products.
- Understanding fungal meroterpenoids is crucial for discovering new bioactive compounds.
Purpose of the Study:
- To review the isolation and structure elucidation of fungal meroterpenoids.
- To discuss biosynthetic pathways and biological activities of these compounds.
- To provide a comprehensive catalog of known fungal meroterpenoids.
Main Methods:
- Literature review of scientific publications.
- Analysis of reported isolation and structure elucidation techniques.
- Compilation of data on biosynthesis and bioactivity.
Main Results:
- Detailed description of 333 fungal meroterpenoids.
- Summary of structural diversity and biosynthetic origins.
- Overview of reported biological activities.
Conclusions:
- Fungi represent a significant source of structurally diverse meroterpenoids.
- Further research into fungal meroterpenoids may yield novel bioactive molecules.
- This review serves as a valuable resource for researchers in natural product chemistry and mycology.
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