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NMR assignment of the domain 513-651 from the SARS-CoV nonstructural protein nsp3
Amarnath Chatterjee1, Margaret A Johnson, Pedro Serrano
1Department of Molecular Biology, The Scripps Research Institute, La Jolla, CA 92037, USA.
Biomolecular NMR Assignments
|July 29, 2009
Abstract:
Sequence-specific NMR assignments of an internal domain of the protein nsp3, nsp3(513-651), which is a part of the SARS coronavirus (SARS-CoV) replicase polyprotein, have been determined, using triple-resonance NMR experiments with the uniformly [(13)C,(15)N]-labeled protein. The complete assignments (>99%) provide the basis for the ongoing three-dimensional structure determination.
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