Cortical mapping and resection under local anaesthetic as an aid to surgery of low and intermediate grade gliomas
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Updated: Oct 14, 2026

Translational Brain Mapping at the University of Rochester Medical Center: Preserving the Mind Through Personalized Brain Mapping
Published on: August 12, 2019
A R Walsh1, R H Schmidt, H T Marsh
1Department of Neurosurgery, Atkinson Morley's Hospital, London, UK.
Abstract:
We report four cases of the use of per-operative cortical mapping during craniotomy under local anaesthesia to define the relationship between the glioma and speech and somatosensory cortex. This enabled a radical subtotal (two cases) or an apparent total (two cases) excision of the tumour close to somatosensory and speech cortex with no permanent neurological deficit. Use of this technique allows radical excision of intrinsic low and intermediate grade gliomas that would otherwise be considered unexcisable and may lead to an improved survival.

